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ea0032oc3.4 | Thyroid | ECE2013

DNA methylation signatures identify biologically distinct thyroid cancer subtypes

Fernandez-Morera Juan Luis , Rodriguez-Rodero Sandra , Alvarez Elias Delgado , Fernandez-Fernandez Agustin , Fernandez-Vega Ivan , Gonzalez-Marquez Rocio , Sanchez-Rivas Veronica , Suarez-Gutierrez Lorena , Rodriguez Caballero Maria Galiana , Blanco Jessica Ares , Fernandez-Fraga Mario , Menendez-Torre Edelmiro

Introduction: The global patterns of aberrant DNA methylation in thyroid cancer are not known. In this study, we have used DNA methylation arrays to determine, for the first time, the genome-wide promoter methylation status of different subtypes of thyroid tumors.Material and methods: We analyzed a cohort of 54 snap frozen thyroid samples (thirteen papillary tumors, six follicular, eleven anaplastic, twenty medullar and four normal tissue samples). Also ...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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